Laboratory of Brain Imaging is a core facility at Nencki Institute. LOBI provides access to cutting edge research support and technologies for internal and external customers. The core technologies being developed and used at the Laboratory are magnetic resonance imaging (MRI), spectroscopy (MRS), electroencephalograpy (EEG - including EEG-fMRI simultaneous recordings), Transcranial Magnetic Stimulation (TMS) and computational image analysis.
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New publication!

New publication from LOBI. Molendowska M., Matuszewski J....and Marchewka A. Temporal Dynamics of Brain White Matter Plasticity in Sighted Subjects during Tactile Braille Learning: A Longitudinal Diffusion Tensor Imaging Study. Throughout the lifetime the human brain is shaped by various experiences. Training-induced reorganization in white matter (WM) microstructure has been reported, but we know little about its temporal dynamics. To fill this gap, we scanned sighted subjects five times during tactile braille reading training. We observed different dynamics of WM plasticity in the somatosensory and visual cortices implicated in braille reading. The former showed a continuous increase in WM tissue anisotropy along with tactile training, while microstructural changes in the latter were observed only after the participants learned to read braille words. Our results confirm the supply–demand model of brain plasticity and provide evidence that WM reorganization depends on distinct computational demands and functional roles of regions involved in the trained skill.

We are happy to welcome Kalina Burnat and her team in LOBI

After great years at the Neuroplasticity Lab with Profesor Małgosia Kossut team, Kalina is moving her research from animal models of visual neuroplasticity to human clinical research and MRI environment at LOBI. In her team, Anna Kozak is involved in DTI analysis of neuroplasticity events upon retinal injury. Together with Marco Ninghetto they evaluated our novel acuity task based on motion perception (Kozak et al., 2021). Thanks to National Science Centre funding in consortium with Professor Jacek Szaflik, director of one of the major ophthalmological hospitals in Warsaw, Poland (Samodzielny Publiczny Kliniczny Szpital Okulistyczny), we explore the cortical reorganization triggered by retinal degenerations, Retinitis Pigmentosa and Stargardt disease.

Polish Returns Programme at the Nencki Institute

Dr Maciej Jurynczyk has obtained funding from the Polish Returns programme of the Polish National Agency for Academic Exchange to create a research group in the Laboratory of Brain Imaging at the Nencki Institute. His research project will aim at developing novel methods of magnetic resonance imaging to improve the diagnosis in patients with atypical forms of CNS demyelination. These patients are often challenging to diagnose while optimal diagnosis is essential as it allows to choose appropriate treatment and prevent long-term disability. Dr Jurynczyk will be able to use his several year research experience obtained in Nuffield Department of Clinical Neurosciences at the University of Oxford where he was involved in a number of pioneer studies aimed at optimising methods of differential diagnosis between multiple sclerosis, neuromyelitis optica and MOG-antibody associated disease.

Doctoral Candidates awarded with the ETIUDA grant.

Congratulations to Maria Kulesza and Jan Szczypiński, who were awarded with the ETIUDA grant sponsored by National Science Center!

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